Bronchial Thermoplasty for Severe Asthma with Mucus Hypersecretion

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Bronchial thermoplasty in asthma.

In this review we discuss the potential of a new procedure, termed Bronchial Thermoplasty to prevent serious consequences resulting from excessive airway narrowing. The most important factor in minimizing an asthmatic attack is limiting the degree of smooth muscle shortening. The premise that airway smooth muscle can be either inactivated or obliterated without any long-term alteration of other...

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Indications for the use of bronchial thermoplasty in severe asthma.

Approximately 5% of the ~3 million asthmatics in South Africa have severe asthma that is associated with substantial morbidity, cost, absenteeism, preventable mortality, and the requirement for costly chronic medication that may be associated with significant adverse events. There is an unmet need for alternative safer and more effective interventions for severe asthma. A recently introduced op...

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Bronchial thermoplasty: a novel therapeutic approach to severe asthma.

Bronchial thermoplasty is a non-drug procedure for severe persistent asthma that delivers thermal energy to the airway wall in a precisely controlled manner to reduce excessive airway smooth muscle. Reducing airway smooth muscle decreases the ability of the airways to constrict, thereby reducing the frequency of asthma attacks. Bronchial thermoplasty is delivered by the Alair System and is perf...

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Bronchial thermoplasty in asthma: current perspectives

Bronchial thermoplasty (BT) is a novel therapy for patients with severe asthma. Using radio frequency thermal energy, it aims to reduce the airway smooth muscle mass. Several clinical trials have demonstrated improvements in asthma-related quality of life and a reduction in the number of exacerbations following treatment with BT. In addition, recent data has demonstrated the long-term safety of...

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Cost effectiveness of bronchial thermoplasty in patients with severe uncontrolled asthma.

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2019

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.1730-18